IV infusions of anesthetics have been shown to promote neuron growth in the brain within just one hour. Many researchers studying ketamine are focusing on the neurotransmitter glutamate, which is crucial for brain activation. Ketamine has also been discovered to have powerful anti-inflammatory properties, which are being explored for its benefits in pain relief. While scientists are still working to understand exactly how it works, the life-changing results are observed every day at ketamine clinics across the U.S.

An infusion is a method of giving medication, like ketamine, through an IV (a tube placed into a vein) over a set amount of time. For depression-related treatments, each infusion usually lasts between 40-60 minutes. For pain-related conditions, the infusion time is generally around 2 hours.

Ketamine infusion treatments are completely legal and follow strict clinical guidelines and oversight. Since ketamine is a relatively new therapy, we understand that there may be existing misconceptions about its use for conditions like depression and chronic pain. However, research and positive patient results have highlighted the benefits of ketamine treatments, bringing hope to those seeking relief. For more information, please check out our research tab to explore the significant and reputable studies conducted on ketamine infusions.

Ketamine has been shown to safely treat various types of resistant depression, including bipolar disorder, seasonal affective disorder, post-partum depression, OCD, severe anxiety, and PTSD. It can also have a quick effect on reducing suicidal thoughts. Additionally, ketamine is effective for managing chronic pain conditions, such as refractory migraines, fibromyalgia, CRPS, and neuropathic pain. However, it is not recommended for use during manic phases or in cases of psychotic disorders like schizophrenia.

Many patients start to feel better during the treatment itself. Others might notice a significant improvement in their mood or pain levels within hours or by the next day. For some, the full benefits might not be apparent until their fourth infusion. While patients may still experience both good and bad days during or after the ketamine infusions, overall improvement is generally observed with continued treatment.

The length of treatment varies for each patient. The first treatment may relieve symptoms for a few days, but repeated treatments are often necessary to achieve lasting relief or to maintain a healthy mood over a longer period. For chronic conditions, we extend the remission period by gradually increasing the time between ketamine infusions and incorporating additional wellness techniques. This approach can vary from patient to patient. Multiple infusions can offer relief ranging from a few weeks to several months. While some patients may notice a decrease in the positive effects of ketamine over time, they still report overall improvement in their lifestyle and coping skills compared to before the treatments. There isn’t a one-size-fits-all therapy for ketamine infusions, but ongoing research has led to best practice protocols.

Research indicates that consecutive infusions, rather than a single dose, are more effective. This is known as the stabilization period, which enhances the growth of dendrites and synapse connections in the brain. After this period, some patients may receive maintenance or “booster” infusions based on their individual needs and returning symptoms. Each patient’s response to treatment can vary, so at Serenity Health, we personalize each care plan. Ketamine is a treatment, not a cure, with a success rate of around 80% for depression and approximately 50% for pain relief.

Side effects from ketamine infusions typically subside within an hour after treatment. Common side effects include mild nausea, drowsiness, and a temporary rise in blood pressure. If necessary, IV medications can be administered to manage any unpleasant symptoms. The clinical staff will carefully monitor your blood pressure and heart rate during and after the infusion. Less common side effects, such as vivid dreams, mood swings, or agitation, can be managed by adjusting the ketamine dosage if they occur.

Ketamine is not currently FDA-approved for treating depression or chronic pain, so it is not covered by insurance. However, some insurance plans may reimburse a portion of the cost per infusion. At Serenity Health, we have a Patient Care Advocate on site who can assist you with insurance forms and help you navigate the process of obtaining reimbursement for your treatments.

To streamline your first visit, please fill out our health history questionnaire online if possible. If you can’t complete it online, download and fill out the form, and bring it with you to your consultation. If you have been referred, we will also need a referral form from your provider. Before your first consultation, please submit the following:

• Most recent lab work from the past 6 months (CBC, CMP) for review during your appointment.
• Any imaging related to your diagnosis (to explain why you are being seen).
• A list of your health history and diagnoses.
• An updated list of your medications.

Your physician can also fax this information to us if needed.

We treat patients aged 16-17 with a specific referral and order from a psychiatrist for depressive syndromes. For all other cases, we treat patients aged 18 and older. If you have any specific questions about this, please call our office.

Never discontinue any medications without prior authorization from your prescribing provider. Some medications can interact with ketamine, and these will be reviewed during your initial consultation. We will conduct a thorough history and medication review, along with a full examination. At Serenity Health, our priority is to ensure your safety and confirm that ketamine infusions are appropriate for you. If you are taking any medications that may interact with ketamine, we will coordinate with your physician and discuss any necessary adjustments to your treatment plan

• Uncontrolled Blood Pressure: Individuals with uncontrolled high blood pressure are at greater risk of worsening their condition during ketamine infusions, which could lead to heart attacks or strokes. It’s important to have blood pressure under control by visiting a family doctor or cardiologist before starting ketamine treatment.

• Heart Disease: People with unstable heart conditions, such as uncontrolled arrhythmias, congestive heart failure, or coronary artery disease, may face increased risks during ketamine infusions since it can cause the heart to pump harder. While these conditions don’t exclude someone from treatment, regular follow-ups with a family physician and cardiologist are crucial, and consultation before treatment is necessary to ensure safety.

• Uncontrolled Thyroid Disease: Ketamine can increase heart rate, potentially worsening uncontrolled thyroid disease. However, individuals with well-controlled thyroid conditions are not affected.

• Glaucoma & Increased Intraocular Pressure: There is a slight risk of elevated intraocular pressure with ketamine at surgical doses. However, the dose used in infusions for mental health or pain is much smaller, and the effects on eye pressure at this dosage are not well understood.

• Hallucinations or Schizophrenia: Ketamine may worsen active hallucinations and anxiety, so it’s not recommended for individuals currently experiencing these symptoms.

• Active Substance Abuse: Ketamine is used to treat addiction, but infusions are typically administered after the patient has detoxed or is no longer using the substances they were addicted to. Using multiple drugs can make the body’s response to ketamine unpredictable and potentially dangerous.

• Ketamine Allergies: Anyone who has had an allergic reaction to ketamine in the past is not a candidate for treatment.